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The HLA FactsBook (Factsbook)
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Binding: Paperback
Dewey Decimal Number: 616.0792
EAN: 9780125450256
Edition: 1st
ISBN: 0125450257
Label: Academic Press
Manufacturer: Academic Press
Number Of Items: 1
Number Of Pages: 398
Publication Date: January 15, 2000
Publisher: Academic Press
Studio: Academic Press
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Editorial Review: The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity.Key Features * Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists * Up-to-date, complete listing of HLA alleles * Invaluable reference resource for immunologists, geneticists, and cell biologists * Combines both structural and functional information, which has never been compiled in a single reference book previously * Serological specificity of allotypes * Identity of material sequenced including ethnic origin * Database accession numbers * Population distribution * Peptide binding specificities * T cell epitopes * Amino acid sequences of allotypes * Key references
Customer Reviews
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Rating: - A Must Have
Any immunologists and virologists interested in identifying antigenic epitopes for vaccine development need this book to guide them.
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