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Prepared by residents and fellows and reviewed by clinical faculty at the Washington University School of Medicine, this handbook is a practical quick-reference guide to the diagnosis and treatment of hematologic disorders and adult malignancies. It covers both inpatient and outpatient management approaches with the same front-lines practicality as the world-famous Washington Manual(R) of Medical Therapeutics. This thoroughly updated Second Edition includes new standards in the treatment of malignancies, mechanisms of action of new therapeutic agents, and the current use of molecular prognostic factors. Key points about diagnosis and management of disorders are bulleted for easy reference. This edition also includes illustrations. The Washington Manual(R) is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.